The prevalence of asymptomatic neurosyphilis among HIV-negative serofast patients in China: A meta-analysis.

ABSTRACT:

Introduction

Neurosyphilis can occur at any stage of syphilis. After treatment, 30%-40% of syphilis patients remained serofast. But the prevalence of asymptomatic neurosyphilis (ANS) among serofast syphilis patients remains unclear. Untimely treatment or improper management for ANS may result in neurological complications. So we perform the meta-analysis to evaluate the prevalence of ANS cases among HIV-negative serofast syphilis patients for exploring their relationship and addressing their clinical management.

Methods

We searched CNKI, Wan Fang, VIP, CBMdisc, PubMed, Embase and Medline from January 1st 1990 to September 22nd 2020 for both English and Chinese records. We strictly restrict the eligibility criteria. STROBE was used for reporting quality assessment. We examine

SUBMITTER: Tan X 

PROVIDER: S-EPMC7641405 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature