Joint Hypermobility Syndrome in Patients With Functional Dyspepsia.

ABSTRACT:

Introduction

The pathophysiology underlying functional dyspepsia (FD) is multifactorial and focuses on gastric sensorimotor dysfunction. Recent studies demonstrated that joint hypermobility syndrome (JHS) is strongly associated with unexplained dyspeptic symptoms in patients attending gastrointestinal clinics. We aimed to study the relationship between symptoms, gastric sensorimotor function, and JHS in FD patients.

Methods

Tertiary care FD patients who underwent a gastric barostat study and a gastric emptying breath test with 13C-octanoic acid were recruited for assessment of JHS. The presence of JHS was evaluated by a 2-phase interview and clinical examination that included major and minor criteria of the Brighton classification.

Results

A total of 62 FD patients (6

SUBMITTER: Carbone F 

PROVIDER: S-EPMC7641428 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature