Cross-Inhibitor: a time-sensitive molecular circuit based on DNA strand displacement.

ABSTRACT: Designing biochemical systems that can be effectively used in diverse fields, including diagnostics, molecular computing and nanomachines, has long been recognized as an important goal of molecular programming and DNA nanotechnology. A key issue in the development of such practical devices on the nanoscale lies in the development of biochemical components with information-processing capacity. In this article, we propose a molecular device that utilizes DNA strand displacement networks and allows interactive inhibition between two input signals; thus, it is termed a cross-inhibitor. More specifically, the device supplies each input signal with a processor such that the processing of one input signal will interdict the signal of the other. Biochemical experiments are conducted to analyze the

SUBMITTER: Liu C 

PROVIDER: S-EPMC7641751 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature