Medical research and reproductive medicine in an ethical context: a critical commentary on the paper dealing with uterine lavage published by Munne et al.

ABSTRACT: A recent study published in Human Reproduction claimed that uterine lavage offers a non-surgical, minimally invasive strategy for the recovery of human embryos from fertile women who do not want or need IVF for medical reasons but who desire preimplantation genetic testing (PGT) for embryos. To prove this hypothesis, the researchers recruited dozens of young Mexican women. The prospective oocyte donors underwent ovarian stimulation to induce the production of multiple mature oocytes. Subsequently, these women were inseminated by donor semen. A few days later, the developing embryos were collected by uterine lavage (uterine flushing) and subjected to genetic testing for aneuploidies (PGT-A). Oocyte donors with persistently elevated hCG levels, indicating the implantation of one or more embr

SUBMITTER: Murtinger M 

PROVIDER: S-EPMC7642030 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature