Ambulatory blood pressure in patients with systemic lupus erythematosus: Association with markers of immune activation.

ABSTRACT: Objectives: Ambulatory blood pressure monitoring measures 24-hour blood pressure, night-time blood pressure, and impaired dipping of nocturnal blood pressure, parameters that better predict cardiovascular risk than standard office blood pressure measurements. Systemic lupus erythematosus is characterized by immune system hyperactivity, elevated cardiovascular risk and high prevalence of hypertension; however, little is known about ambulatory blood pressure in lupus patients and its relationship to immune activation. Methods: We studied 26 patients with lupus and 26 control subjects. We obtained ambulatory 24-hour blood pressure measurements and report plasma concentrations of 77 markers of immune activation using a multiplex immunoassay and assessed their association with blo

SUBMITTER: Carranza-Leon DA 

PROVIDER: S-EPMC7642148 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature