Rampant loss of social traits during domestication of a Bacillus subtilis natural isolate.

ABSTRACT: Most model bacteria have been domesticated in laboratory conditions. Yet, the tempo with which a natural isolate diverges from its ancestral phenotype under domestication to a novel laboratory environment is poorly understood. Such knowledge, however is essential to understanding the rate of evolution, the time scale over which a natural isolate can be propagated without loss of its natural adaptive traits, and the reliability of experimental results across labs. Using experimental evolution, phenotypic assays, and whole-genome sequencing, we show that within a week of propagation in a common laboratory environment, a natural isolate of Bacillus subtilis acquires mutations that cause changes in a multitude of traits. A single adaptive mutational step in the gene coding for the transcriptio

SUBMITTER: Barreto HC 

PROVIDER: S-EPMC7642357 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature