Risk of dengue virus infection according to serostatus in individuals from dengue endemic areas of Mexico.

ABSTRACT: The variability in the host immune response directed against dengue virus (DENV) has demonstrated the need to understand the immune response associated with protection in incident infection. The objective was to estimate the association between serostatus and the risk of incident DENV infection. We used a prospective study from 2014 to 2016 in the localities of Axochiapan and Tepalcingo, Morelos, Mexico. We recruited 966 participants, of which, according to their infection history registered were categorized in four groups. To accomplish the objectives of this study, we selected to 400 participants older than 5 years of age were followed for 2.5 years. Blood samples were taken every 6 months to measure serological status and infection by ELISA. In individuals with at least two previous inf

SUBMITTER: Amaya-Larios IY 

PROVIDER: S-EPMC7642410 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature