Ontology highlight
ABSTRACT:
SUBMITTER: Yan A
PROVIDER: S-EPMC7642909 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Frontiers in cellular and infection microbiology 20201022
While the human gut virome has been increasingly explored in recent years, nearly all studies have been limited to fecal sampling. The mucosal-luminal interface has been established as a viable sample type for profiling the microbial biogeography of the gastrointestinal tract. We have developed a protocol to extract nucleic acids from viruses at the mucosal-luminal interface of the proximal and distal colon. Colonic viromes from pediatric patients with Crohn's disease demonstrated high interpati ...[more]