Evaluation of Outcomes Following Surgery for Locally Advanced Pancreatic Neuroendocrine Tumors.

ABSTRACT:

Importance

Although outcome of surgical resection of liver metastases from pancreatic neuroendocrine tumors (PNETs) has been extensively studied, little is known about surgery for locally advanced PNETs; it was listed recently by the European neuroendocrine tumor society as a major unmet need.

Objective

To evaluate the outcome of patients who underwent surgery for locally aggressive PNETs.

Design, setting, and participants

This retrospective single-center case series reviewed consecutive patients who underwent resection of T3/T4 PNETs at a single academic institution. Data collection occurred from 2003 to 2018. Data analysis was performed in August 2019.

Main outcomes and measures

Disease-free survival (primary outcome) and overall mortality (secondary outcome)

SUBMITTER: Titan AL 

PROVIDER: S-EPMC7643030 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature