Association between coarse particulate matter and inflammatory and hemostatic markers in a cohort of midlife women.

ABSTRACT:

Background

Exposure to particulate matter air pollution has been associated with cardiovascular disease (CVD) morbidity and mortality; however, most studies have focused on fine particulate matter (PM_2.5) exposure and CVD. Coarse particulate matter (PM_10-2.5) exposure has not been extensively studied, particularly for long-term exposure, and the biological mechanisms remain uncertain.

Methods

We examined the association between ambient concentrations of PM_10-2.5 and inflammatory and hemostatic makers that have been linked to CVD. Annual questionnaire and clinical data were obtained from 1694 women (≥ 55 years old in 1999) enrolled in the longitudinal Study of Women's Health Across the Nation (SWAN) at six study sites from 1999 to 2004. Reside

SUBMITTER: Davis E 

PROVIDER: S-EPMC7643259 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature