Analgesic medicines for adults with low back pain: protocol for a systematic review and network meta-analysis.

ABSTRACT:

Background

There is limited evidence for the comparative effectiveness of analgesic medicines for adults with low back pain. This systematic review and network meta-analysis aims to determine the analgesic effect, safety, acceptability, effect on function, and relative rank according to analgesic effect, safety, acceptability, and effect on function of a single course of [an] analgesic medicine(s) or combination of these medicines for people with low back pain.

Methods

We will include published and unpublished randomised trials written in any language that compare an analgesic medicine to either another medicine, placebo/sham, or no intervention in adults with low back pain, grouped according to pain duration: acute (fewer than 6 weeks), sub-acute (6 to 12 weeks), and chroni

SUBMITTER: Wewege MA 

PROVIDER: S-EPMC7643321 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature