Genetic and Environmental Risk Factors for Cannabis Use: Preliminary Results for the Role of Parental Care Perception.

ABSTRACT:

Background

Vulnerability to cannabis use (CU) initiation and problematic use have been shown to be affected by both genetic and environmental factors, with still inconclusive and uncertain evidence.

Objective

Aim of the present study was to investigate the possible interplay between gene polymorphisms and psychosocial conditions in CU susceptibility.

Methods

Ninety-two cannabis users and ninety-three controls have been included in the study. Exclusion criteria were serious mental health disorders and severe somatic disorders, use of other drugs and alcohol abuse; control subjects were not screened to remove Reward Deficiency Syndrome (RDS) behaviors. A candidate gene association study was performed, including variants related to dopaminergic and endocannabinoids pathw

SUBMITTER: Gerra MC 

PROVIDER: S-EPMC7643561 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature