Quality of reporting of cranial irradiation techniques in randomized controlled trials of primary brain tumors: A systematic review.

ABSTRACT:

Background

To assess the quality of reporting of cranial irradiation (CR) techniques in randomized controlled trials (RCTs) of primary brain tumors.

Methods

We searched PubMed and EMBASE for RCTs of primary brain tumors, published from January 1999 to November 2019 which included CR as one of the intervention arms. We assessed the initial RCTs report on whether they reported the prespecified ten criteria for CR technique adequately. Multivariable logistic regression was performed to determine the factors that were predictive of adequate quality of reporting.

Results

We found 85 eligible trial reports. There was significant variability in the quality of reporting among the included studies. Total radiotherapy (RT) dose and fractionation schedule were reported adequatel

SUBMITTER: Tan TH 

PROVIDER: S-EPMC7644083 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature