Insulin signaling represents a gating mechanism between different memory phases in Drosophila larvae.

ABSTRACT: The ability to learn new skills and to store them as memory entities is one of the most impressive features of higher evolved organisms. However, not all memories are created equal; some are short-lived forms, and some are longer lasting. Formation of the latter is energetically costly and by the reason of restricted availability of food or fluctuations in energy expanses, efficient metabolic homeostasis modulating different needs like survival, growth, reproduction, or investment in longer lasting memories is crucial. Whilst equipped with cellular and molecular pre-requisites for formation of a protein synthesis dependent long-term memory (LTM), its existence in the larval stage of Drosophila remains elusive. Considering it from the viewpoint that larval brain structures are completely re

SUBMITTER: Eschment M 

PROVIDER: S-EPMC7644093 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature