Application of micro-dried droplets for quantitative analysis of particulate inorganic samples with LA-ICP-MS demonstrated on surface-modified nanoparticle TiO₂ catalyst materials.

ABSTRACT: A quick, flexible and reliable method was developed, based on laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS), for accurate assessment of nanomaterial composition with sample amounts in the picogram to nanogram range. We demonstrate its capabilities for the analysis of surface-modified TiO₂ nanoparticulate (NP) catalyst materials. For sampling, suspensions of NP were deposited on a substrate material, ablated with a pulsed laser and then analysed using quadrupole ICP-MS. The calibration and quantification approach is based on the use of so-called micro-dried droplets (μDD) as the standard material. To overcome some of the major drawbacks of conventional dried droplet approaches, self-aliquoting wells were used in this work. By mimicking the ablation condi

SUBMITTER: Horak F 

PROVIDER: S-EPMC7644544 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature