Comparative Studies of the Gut Microbiota in the Offspring of Mothers With and Without Gestational Diabetes.

ABSTRACT: Background: Offspring of mothers with gestational diabetes mellitus (GDM) have increased risk of developing metabolic disorders as they grow up. Microbial colonization of the newborn gut and environmental exposures affecting the configuration of the gut microbiota during infancy have been linked to increased risk of developing disease during childhood and adulthood. In a convenience sample, we examined whether the intestinal tract of children born to mothers with GDM is differentially colonized in early life compared to offspring of mothers with normal gestational glucose regulation. Secondly, we examined whether any such difference persists during infancy, thus potentially conferring increased risk of developing metabolic disease later in life. Methods: Fecal samples were co

SUBMITTER: Crusell MKW 

PROVIDER: S-EPMC7645212 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature