Influence of Contrast Administration on Computed Tomography-Based Analysis of Visceral Adipose and Skeletal Muscle Tissue in Clear Cell Renal Cell Carcinoma.

ABSTRACT:

Background

Computed tomography (CT) scans are being utilized to examine the influence of skeletal muscle and visceral adipose quantity and quality on health-related outcomes in clinical populations. However, little is known about the influence of contrast administration on these parameters.

Methods

Precontrast, arterial, and 3-minute postcontrast CT images of 45 patients with clear cell renal cell carcinoma were downloaded from The Cancer Imaging Archive and retrospectively analyzed for visceral adipose cross-sectional area (CSA) and density, and muscle CSA and density at the third lumbar vertebrae. Low muscle CSA index was defined as ≤38.9 cm² /m² for women and ≤55.4 cm² /m² for men. Low muscle density was defined as <41 Hounsfiel

SUBMITTER: Paris MT 

PROVIDER: S-EPMC7645806 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature