Identification and functional characterization of SlDronc in Spodoptera littoralis.

ABSTRACT:

Background

Apoptosis is responsible for eliminating damaged and virus-infected cells, regulating normal cell turnover, and maintaining the immune system's development and function. Caspases play a vital role in both mammal and invertebrate apoptosis. Spodoptera littoralis is a generalist insect herbivore that is one of the most destructive pests in tropical and subtropical areas and attacks a wide range of commercially important crops. Although S. littoralis is a model organism in the study of baculovirus infection, its apoptotic pathway has not been explored.

Methods

We cloned a new caspase gene named sldronc in S. littoralis using Rapid Amplification of cDNA Ends (RACE). We then measured caspase activity on synthetic caspase substrates and S.

SUBMITTER: Liu H 

PROVIDER: S-EPMC7646310 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature