Survival and end-of-life aspects among subjects on long-term noninvasive ventilation.

ABSTRACT:

Background

The need for noninvasive ventilation (NIV) is commonly considered a predictor of poor survival, but life expectancy may vary depending on the underlying disease. We studied the factors associated with decreased survival and end-of-life characteristics in an unselected population of subjects starting NIV.

Methods

We conducted a retrospective study including 205 subjects initiating NIV from 1/1/2012-31/12/2015 who were followed up until 31/12/2017.

Results

The median survival time was shorter in subjects needing help with activities of daily living than in independent subjects (hazard ratio (HR) for death 1.7, 95% CI 1.2-2.6, P = 0.008) and was also shorter in subjects on long-term oxygen therapy (LTOT) than in those not on LTOT (HR for death 2.8, 95%

SUBMITTER: Rantala HA 

PROVIDER: S-EPMC7646568 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature