Using elastic nets to estimate frailty burden from routinely collected national aged care data.

ABSTRACT:

Objectives

To (1) use an elastic net (EN) algorithm to derive a frailty measure from a national aged care eligibility assessment program; (2) compare the ability of EN-based and a traditional cumulative deficit (CD) based frailty measures to predict mortality and entry into permanent residential care; (3) assess if the predictive ability can be improved by using weighted frailty measures.

Materials and methods

A Cox proportional hazard model based EN algorithm was applied to the 2003-2013 cohort of 903 996 participants for selecting items to enter an EN based frailty measure. The out-of-sample predictive accuracy was measured by the area under the curve (AUC) from Cox models fitted to 80% training and validated on 20% testing samples.

Results

The EN approach resulted

SUBMITTER: Moldovan M 

PROVIDER: S-EPMC7647260 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature