The My Cancer Genome clinical trial data model and trial curation workflow.

ABSTRACT:

Objective

As clinical trials evolve in complexity, clinical trial data models that can capture relevant trial data in meaningful, structured annotations and computable forms are needed to support accrual.

Material and methods

We have developed a clinical trial information model, curation information system, and a standard operating procedure for consistent and accurate annotation of cancer clinical trials. Clinical trial documents are pulled into the curation system from publicly available sources. Using a web-based interface, a curator creates structured assertions related to disease-biomarker eligibility criteria, therapeutic context, and treatment cohorts by leveraging our data model features. These structured assertions are published on the My Cancer Genome (MCG) website

SUBMITTER: Jain N 

PROVIDER: S-EPMC7647323 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature