¹H, ¹³C, and ¹⁵N backbone chemical shift assignments of coronavirus-2 non-structural protein Nsp10.

ABSTRACT: The international Covid19-NMR consortium aims at the comprehensive spectroscopic characterization of SARS-CoV-2 RNA elements and proteins and will provide NMR chemical shift assignments of the molecular components of this virus. The SARS-CoV-2 genome encodes approximately 30 different proteins. Four of these proteins are involved in forming the viral envelope or in the packaging of the RNA genome and are therefore called structural proteins. The other proteins fulfill a variety of functions during the viral life cycle and comprise the so-called non-structural proteins (nsps). Here, we report the near-complete NMR resonance assignment for the backbone chemical shifts of the non-structural protein 10 (nsp10). Nsp10 is part of the viral replication-transcription complex (RTC). It aids in synt

SUBMITTER: Kubatova N 

PROVIDER: S-EPMC7648550 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature