Cyclosporine Improves Sleep Quality in Patients with Atopic Dermatitis.

ABSTRACT:

Introduction

Atopic dermatitis (AD) is a chronic, relapsing, inflammatory skin disease characterized by eczema and pruritus, and frequently impairs sleep quality. Although cyclosporine improves symptoms of AD, objective evaluation of sleep in patients with AD treated with cyclosporine has not been reported. This study was conducted to elucidate the effects of cyclosporine on sleep quality for patients with AD.

Methods

Twelve patients with moderate-to-severe AD were recruited. Nocturnal sleep quality was evaluated for 7 days using a sleep analyzer, which patients wore at the waist before and after cyclosporine was administered at 2.0-4.0 mg/kg per day. Seven parameters of sleep quality were measured before and after cyclosporine administration for a period of 7 days for each

SUBMITTER: Yasuda KI 

PROVIDER: S-EPMC7649172 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature