Evolution of Drug Interactions With Antiretroviral Medication in People With HIV.

ABSTRACT:

Background

Polypharmacy and drug interactions are important issues for HIV-infected individuals. The number and nature of those interactions are continuously evolving with the use of new antiretroviral drugs and the aging of HIV-infected individuals. We aimed to analyze this evolution over time.

Methods

This retrospective cohort study was conducted in the University Hospital of Liège (Belgium). Treatments of HIV-infected outpatients attending Liège University Hospital were collected and analyzed in 2012 and 2016. The University of Liverpool HIV drug interactions database was used to determine drug interactions.

Results

We included 1038 patients in 2016, of whom 78% had 1 comedication. Polypharmacy was seen in 20% of the cohort. Four percent of the patients presented r

SUBMITTER: El Moussaoui M 

PROVIDER: S-EPMC7651038 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature