Association between platelet count and hepatocellular carcinoma overall survival: a large retrospective cohort study.

ABSTRACT:

Objectives

To explore the non-linear relationship between platelet count (PLT) and hepatocellular carcinoma (HCC) overall survival (OS).

Setting

The study was done in Sun Yat-sen University Cancer Center (SYSUCC) from January 2007 to May 2012, a total of 5005 consecutive participants at SYSUCC were retrospectively reviewed, and 979 patients with Barcelona clinic liver cancer (BCLC) stage B were selected for the final analysis.

Participants

A total of 979 newly diagnosed patients with HCC with BCLC stage B were identified for the secondary analysis. Eight cases were excluded for missing data of PLT.

Main outcome measures

Cox proportional hazard regression models were used to calculate multivariable-adjusted HRs and 95% CIs for HCC. The non-linear relationship wa

SUBMITTER: Lu L 

PROVIDER: S-EPMC7651714 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature