Kinetic changes in virology, specific antibody response and imaging during the clinical course of COVID-19: a descriptive study.

ABSTRACT:

Background

To explore the kinetic changes in virology, specific antibody response and imaging during the clinical course of COVID-19.

Methods

This observational study enrolled 20 patients with COVID-19, who were hospitalized between January 20-April 6, 2020, in the two COVID-19 designated hospitals of Zhoushan, Zhejiang and Rushan, Shandong, China, The laboratory findings, imaging, serum response to viral infection, and viral RNA level in the throat and stool samples were assessed from onset to recovery phase in patients with COVID-19.

Results

SARS-COV-2 RNA was positive as early as day four. It remained positive until day 55 post-onset in the sputum-throat swabs and became negative in most cases (55%) within 14 days after onset. Lymphocytopenia occurred in 40% (8/20)

SUBMITTER: Wang QJ 

PROVIDER: S-EPMC7652587 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature