Association between high fatty liver index and development of colorectal cancer: a nationwide cohort study with 21,592,374 Korean.

ABSTRACT:

Background/aims

In Korea, the incidence of colorectal cancer (CRC) and nonalcoholic fatty liver disease (NAFLD) has increased due to a westernized lifestyle. This study investigated whether a high fatty liver index that reflects NAFLD correlates with CRC.

Methods

Data from the National Health Insurance Corporation 2009 to 2012 were analyzed. NAFLD disease was defined as a fatty liver index > 60 in the absence of alcohol consumption of ≥ 30 g/day.

Results

NAFLD was identified in 2,543,649 (11.8%) of 21,592,374 participants. CRC was identified in 19,785 (0.8%) of participants with NAFLD (fatty liver index ≥ 60) and in 80,871 (0.6%) participants without NAFLD (fatty liver index < 30). Multivariate logistic regression analysis demonstrated an independent association betwe

SUBMITTER: Choi YJ 

PROVIDER: S-EPMC7652640 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature