J-curve relationship between corrected QT interval and mortality in acute heart failure patients.

ABSTRACT:

Background/aims

This study investigated the prognostic power of corrected QT (QTc) interval in patients with acute heart failure (AHF) according to sex.

Methods

We analyzed multicenter Korean Acute Heart Failure registry with patients with AHF admitted from 2011 to 2014. Among them, we analyzed 4,990 patients who were followed up to 5 years. Regarding QTc interval based on 12 lead electrocardiogram, patients were classified into quartiles according to sex.

Results

During follow-up with median 43.7 months, 2,243 (44.9%) patients died. The relationship between corrected QT interval and all-cause mortality followed a J-curve relationship. In Kaplan-Meier analysis, both sex had lowest mortality in the second QTc quartile. There were significant prognostic differences betw

SUBMITTER: Park CS 

PROVIDER: S-EPMC7652667 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature