Assessing the protective effects of different surface coatings on NaYF₄:Yb³⁺, Er³⁺ upconverting nanoparticles in buffer and DMEM.

ABSTRACT: We studied the dissolution behavior of β NaYF₄:Yb(20%), Er(2%) UCNP of two different sizes in biologically relevant media i.e., water (neutral pH), phosphate buffered saline (PBS), and Dulbecco's modified Eagle medium (DMEM) at different temperatures and particle concentrations. Special emphasis was dedicated to assess the influence of different surface functionalizations, particularly the potential of mesoporous and microporous silica shells of different thicknesses for UCNP stabilization and protection. Dissolution was quantified electrochemically using a fluoride ion selective electrode (ISE) and by inductively coupled plasma optical emission spectrometry (ICP OES). In addition, dissolution was monitored fluorometrically. These experiments revealed that a thick microporous si

SUBMITTER: Saleh MI 

PROVIDER: S-EPMC7652843 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature