Directionality of Genital Human Papillomavirus Infection Transmission Within Heterosexual Couples: A Systematic Review and Meta-analysis.

ABSTRACT:

Background

Limited evidence indicates greater female-to-male (F-M) transmission of genital infection with human papillomavirus (HPV) relative to male-to-female (M-F). We verified the hypothesis of a differential transmission rate in couple-based studies by conducting a systematic review and meta-analysis.

Methods

We searched MEDLINE, EMBASE, Scopus, and Cochrane Library databases for studies published until December 2019. We calculated pooled estimates of F-M and M-F transmission rates and their rate differences per 100 person-months, with 95% confidence intervals (CI), using a random-effects model. We counted occurrences of directionality preponderance for each HPV type.

Results

We identified 7 eligible studies published between 2008 and 2019, providing data for 752

SUBMITTER: Balaji R 

PROVIDER: S-EPMC7653088 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature