Optic neuropathy as a presenting feature of vitamin B-12 deficiency: A systematic review of literature and a case report.

ABSTRACT:

Introduction

Vitamin B12 (VitB12) deficiency rarely manifests with visual symptoms. Optic nerve damage in VitB12 deficiency is thought to be via degeneration. However, optic neuritis, though infrequent, has been reported secondary to VitB12 deficiency.

Material and methods

We conducted a systematic review of all the reported cases of VitB12 deficiency with optic nerve involvement in Pubmed, Cochrane, and Google Scholar any date up to September 6, 2020. We have discussed the findings and compiled the available information on ophthalmological manifestations of VitB12 deficiency. We aim to provide a unified knowledge about the evidence related to types of optic neuropathies reported to date secondary to VitB12 deficiency. We also present a case of bilateral optic neuritis secon

SUBMITTER: Ata F 

PROVIDER: S-EPMC7653199 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature