Revealing oral microbiota composition and functionality associated with heavy cigarette smoking.

ABSTRACT:

Background

Heavy tobacco smoking, a hallmark feature of lung cancer, is drastically predominant in Middle Eastern populations. The precise links between nicotine dependence and the functional contribution of the oral microbiota remain unknown in these populations.

Methods

We evaluated the composition and functional capabilities of oral microbiota with relation to cigarette smoking in 105 adults through shotgun metagenomics using buccal swabs.

Results

The oral microbiota composition in our study subjects was dominated by the phyla Firmicutes, Proteobacteria, Actinobacteria, and Bacteroidetes, in addition to the genera Prevotella and Veillonella, similar to previously described westernized cohorts. Furthermore, the smoker's oral microbiota represented a significant abun

SUBMITTER: Al Bataineh MT 

PROVIDER: S-EPMC7653996 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature