Study protocol: Whole genome sequencing Implementation in standard Diagnostics for Every cancer patient (WIDE).

ABSTRACT:

Background

'Precision oncology' can ensure the best suitable treatment at the right time by tailoring treatment towards individual patient and comprehensive tumour characteristics. In current molecular pathology, diagnostic tests which are part of the standard of care (SOC) only cover a limited part of the spectrum of genomic changes, and often are performed in an iterative way. This occurs at the expense of valuable patient time, available tissue sample, and interferes with 'first time right' treatment decisions. Whole Genome Sequencing (WGS) captures a near complete view of genomic characteristics of a tumour in a single test. Moreover, WGS facilitates faster implementation of new treatment relevant biomarkers. At present, WGS mainly has been applied in study settings, but its pe

SUBMITTER: Samsom KG 

PROVIDER: S-EPMC7654005 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature