Optimization of DARTEL Settings for the Detection of Alzheimer Disease.

ABSTRACT: BACKGROUND AND PURPOSE:Although Diffeomorphic Anatomical Registration Through Exponentiated Lie Algebra (DARTEL) has been introduced as an alternative to conventional voxel-based morphometry, there are scant data available regarding the optimal image-processing settings. The aim of this study was to optimize image-processing and ROI settings for the diagnosis of Alzheimer disease using DARTEL. MATERIALS AND METHODS:Between May 2002 and August 2014, we selected 158 patients with Alzheimer disease and 198 age-matched healthy subjects; 158 healthy subjects served as the control group against the patients with Alzheimer disease, and the remaining 40 served as the healthy data base. Structural MR images were obtained in all the participants and were processed using DARTEL-based voxel-based morp

SUBMITTER: Komatsu J 

PROVIDER: S-EPMC7655334 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature