Correlation of Serum BACE1 With Emergence Delirium in Postoperative Patients: A Preliminary Study.

ABSTRACT: Background: The mechanism underlying delirium, a common acute fluctuating mental state, may be related to the activation of a neuroinflammatory response. In this study, we attempted to investigate whether plasma inflammatory response markers, vascular and cerebrovascular injury-related markers, and neurodegeneration-associated markers were associated with emergence delirium (ED). Methods: Patients aged 50 years or above who underwent elective laparoscopic surgery under general anesthesia were included in this study. Delirium was assessed postoperatively with the Richmond Agitation Sedation Scale (RASS) and the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) scale. Plasma samples were collected from ED patients and non-ED patients to test concentrations of in

SUBMITTER: Ye C 

PROVIDER: S-EPMC7655534 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature