Spectacle: An interactive resource for ocular single-cell RNA sequencing data analysis.

ABSTRACT: Single-cell RNA sequencing has revolutionized ocular gene expression studies. This technology has enabled researchers to identify expression signatures for rare cell types and characterize how gene expression changes across biological conditions, such as topographic region or disease status. However, sharing single-cell RNA sequencing results remains a major obstacle, particular for individuals without a computational background. To address these limitations, we developed Spectacle, an interactive web-based resource for exploring previously published single-cell RNA sequencing data from ocular studies. Spectacle is powered by a locally developed R package, cellcuratoR, which utilizes the Shiny framework in R to generate interactive visualizations for single-cell expression data. Spectacle

SUBMITTER: Voigt AP 

PROVIDER: S-EPMC7655596 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature