Glycated Hemoglobin A_1c, Lung Function, and Hospitalizations Among Adults with Asthma.

ABSTRACT:

Background

Insulin resistance and metabolic dysfunction have been associated with asthma risk and asthma severity.

Objective

To examine the association between glycated hemoglobin A_1c (HbA_1c), asthma-related hospitalizations, and lung function measures among adults in the United Kingdom.

Methods

A cross-sectional study was conducted of 47,606 adults aged 40 to 69 years who participated in the UK Biobank and had asthma but no diagnosis of diabetes mellitus. HbA_1c level was analyzed as a continuous measure and also categorized as normal (<42 mmol/mol) or as consistent with prediabetes/diabetes (≥42 mmol/mol). An asthma-related hospitalization was defined as ever having had a hospitalization with an International Classification of Disease

SUBMITTER: Yang G 

PROVIDER: S-EPMC7655696 | biostudies-literature | 2020 Nov - Dec

REPOSITORIES: biostudies-literature