Effect of e-Cigarettes Plus Counseling vs Counseling Alone on Smoking Cessation: A Randomized Clinical Trial.

ABSTRACT:

Importance

Electronic cigarettes (e-cigarettes) for smoking cessation remain controversial.

Objective

To evaluate e-cigarettes with individual counseling for smoking cessation.

Design, setting, and participants

A randomized clinical trial enrolled adults motivated to quit smoking from November 2016 to September 2019 at 17 Canadian sites (801 individuals screened; 274 ineligible and 151 declined). Manufacturing delays resulted in early termination (376/486 participants, 77% of target). Outcomes through 24 weeks (March 2020) are reported.

Interventions

Randomization to nicotine e-cigarettes (n = 128), nonnicotine e-cigarettes (n = 127), or no e-cigarettes (n = 121) for 12 weeks. All groups received individual counseling.

Main outcomes and measures

The prim

SUBMITTER: Eisenberg MJ 

PROVIDER: S-EPMC7656286 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature