Recycling the Purpose of Old Drugs to Treat Ovarian Cancer.

ABSTRACT: The main challenge in ovarian cancer treatment is the management of recurrences. Facing this scenario, therapy selection is based on multiple factors to define the best treatment sequence. Target therapies, such as bevacizumab and polymerase (PARP) inhibitors, improved patient survival. However, despite their achievements, ovarian cancer survival remains poor; these therapeutic options are highly costly and can be associated with potential side effects. Recently, it has been shown that the combination of repurposed, conventional, chemotherapeutic drugs could be an alternative, presenting good patient outcomes with few side effects and low costs for healthcare institutions. The main aim of this review is to strengthen the importance of repurposed drugs as therapeutic alternatives, and to pr

SUBMITTER: Nunes M 

PROVIDER: S-EPMC7656306 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature