Difference in inflammation, atherosclerosis, and platelet activation between coronary artery aneurysm and coronary artery ectasia.

ABSTRACT:

Background

Coronary artery aneurysm (CAA) and coronary artery ectasia (CAE) may be two different types of coronary artery dilatation with unknown etiology. This study aimed to compare the differences between CAA and CAE and to investigate their pathogenesis and the necessity of antiplatelet therapy.

Methods

One hundred patients each with confirmed CAA, CAE, and normal coronary artery (NCA) from September 2017 to July 2019 were included. All patients completed examinations of the ankle-brachial index (ABI), pulse wave rate, and carotid ultrasonography; and were tested for routine blood, lipid, and immune parameters. Blood samples were collected 1 week after the withdrawal of antiplatelet drugs, and vascular inflammatory indexes, platelet activation indexes, thromboelastograph

SUBMITTER: Wei W 

PROVIDER: S-EPMC7656333 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature