A new lung donor score to predict short and long-term survival in lung transplantation.

ABSTRACT:

Background

Donor selection criteria are crucial for a successful lung transplant outcome. Our objective was to develop a new donor score to predict short- and long-term survival and validate it with five existing lung donor scores (Oto, Eurotransplant, Minnesota, Maryland-UNOS, Louisville-UNOS).

Methods

All 454 adult lung transplants at our center between 1992-2015 were included to develop a new score. Discriminative ability for all scores was calculated by the area under time-dependent receiver operating characteristic curves (time-dependent AUC) at 30-day, 1, 5 and 10-year survival, and their fit compared with Akaike's information criterion. For the new score, five pre-selected donor risk factors were derived: age, diabetes mellitus, smoking history, pulmonary infection, P

SUBMITTER: Ehrsam JP 

PROVIDER: S-EPMC7656336 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature