Adaptive venom evolution and toxicity in octopods is driven by extensive novel gene formation, expansion, and loss.

ABSTRACT:

Background

Cephalopods represent a rich system for investigating the genetic basis underlying organismal novelties. This diverse group of specialized predators has evolved many adaptations including proteinaceous venom. Of particular interest is the blue-ringed octopus genus (Hapalochlaena), which are the only octopods known to store large quantities of the potent neurotoxin, tetrodotoxin, within their tissues and venom gland.

Findings

To reveal genomic correlates of organismal novelties, we conducted a comparative study of 3 octopod genomes, including the Southern blue-ringed octopus (Hapalochlaena maculosa). We present the genome of this species and reveal highly dynamic evolutionary patterns at both non-coding and coding organizational levels. Gene family expansions previ

SUBMITTER: Whitelaw BL 

PROVIDER: S-EPMC7656900 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature