Morning diurnal preference and food intake: a Mendelian randomization study.

ABSTRACT:

Background

Poor dietary choices may underlie known associations between having an evening diurnal preference and cardiometabolic diseases. Assessing causal links between diurnal preference and food intake is now possible in Mendelian randomization (MR) analyses.

Objectives

We aimed to use a 2-sample MR to determine potential causal effects of genetic liability to a morning preference on food intake. We also examined potential causal effects of a morning preference on objectively captured response performances to email-administered 24-h diet recalls.

Methods

We used genetic variants associated with a morning preference from a published genome-wide association meta-analysis. Our outcomes included 61 food items with estimates from a food-frequency questionnaire in the UK

SUBMITTER: Dashti HS 

PROVIDER: S-EPMC7657324 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature