Utility of platelet indices in alcoholic hepatitis: a retrospective study.

ABSTRACT:

Background

The commonly available platelet indices are platelet distribution width (PDW), plateletcrit (PCT), and mean platelet volume (MPV). They have been used in diagnosis and prognosis of various abdominal disorders. They have never been used to predict severity of alcoholic hepatitis.

Methods

A retrospective analysis of chronic alcohol consumers presenting with jaundice and deranged liver function tests was performed. Maddrey discriminant function (MDF) and modified end-stage liver disease (MELD) scores were calculated and patients compared between severe and nonsevere alcoholic hepatitis (MDF ≥32 vs MDF <32 and MELD >20 vs MELD ≤20). Logistic regression analysis was performed to find significant predictors. Receiver operating characteristic was used to find the area un

SUBMITTER: Vijayakumar S 

PROVIDER: S-EPMC7657577 | biostudies-literature | 2020 Sep-Oct

REPOSITORIES: biostudies-literature