A urine-based biomarker for chronic prostatitis/chronic pelvic pain syndrome: a retrospective multi-center study.

ABSTRACT:

Background

Chronic prostatitis (CP) or chronic pelvic pain syndrome (CPPS) is one of the most common diseases in young and middle-aged men, accounting for 30% of outpatient men in urology OPD. There are no definitive diagnostic criteria for CP or CPPS and no accepted therapies that cure the disease.

Methods

We identified 372 patients with CP diagnosed from 2015 to 2018 and collect the information of age, routine urinary test, express prostatic secretion (EPS), and NIH-Chronic Prostatitis Symptom Index (NIH-CPSI).

Results

Our study proved a correlation between the increase of prostatic exosomal proteins (PSEPs) level and NIH-CPSI scores. Spearman's correlation coefficient showed a significant level correlation between NIH-CPSI and PSEP level (rs=0.194, P=0.0035). In th

SUBMITTER: Liang W 

PROVIDER: S-EPMC7658121 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature