Quantitative Analysis of Macular Retina Using Light Reflection Indices Derived from SD-OCT for Pituitary Adenoma.

ABSTRACT:

Purpose

To quantitatively investigate the macular retinal light reflection characteristic using optical property indices derived from spectral-domain optical coherence tomography (SD-OCT) scans with depth attenuation compensation for pituitary adenoma.

Methods

This study included 38 patients (mean age 44.66 ± 13.77 years old) with diagnosis of pituitary adenoma and 43 age-matched controls. All SD-OCT scans were light attenuation compensated by a depth-resolved model. Attenuation coefficient, the corrected intensity, and the retinal layer thickness were deduced for macular retinal nerve fiber layer (RNFL) and ganglion cell layer combined with inner plexiform layer (GCIPL), as well as comparing between patients and controls by statistical methods.

Results

Attenuation co

SUBMITTER: Sun M 

PROVIDER: S-EPMC7658689 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature