Effect of Cognitive Prehabilitation on the Incidence of Postoperative Delirium Among Older Adults Undergoing Major Noncardiac Surgery: The Neurobics Randomized Clinical Trial.

ABSTRACT:

Importance

Postoperative delirium in older adults is a common and costly complication after surgery. Cognitive reserve affects the risk of postoperative delirium, and thus preoperative augmentation of reserve as a preventive technique is of vital interest.

Objective

To determine whether cognitive prehabilitation reduces the incidence of postoperative delirium among older adults.

Design, setting, and participants

This was a prospective, single-blinded randomized clinical trial conducted from March 2015 to August 2019 at the Ohio State University Wexner Medical Center in Columbus. Patients 60 years and older undergoing major, noncardiac, nonneurological surgery under general anesthesia, with an expected hospital stay of at least 72 hours, were eligible for trial inclusi

SUBMITTER: Humeidan ML 

PROVIDER: S-EPMC7658803 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature