Ontology highlight
ABSTRACT:
SUBMITTER: Prompsy P
PROVIDER: S-EPMC7658988 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Nature communications 20201111 1
Chromatin modifications orchestrate the dynamic regulation of gene expression during development and in disease. Bulk approaches have characterized the wide repertoire of histone modifications across cell types, detailing their role in shaping cell identity. However, these population-based methods do not capture cell-to-cell heterogeneity of chromatin landscapes, limiting our appreciation of the role of chromatin in dynamic biological processes. Recent technological developments enable the mappi ...[more]