Association Between Ethnicity and Severe COVID-19 Disease: a Systematic Review and Meta-analysis.

ABSTRACT:

Objectives

This article evaluates if ethnicity is an independent poor prognostic factor in COVID-19 disease.

Methods

MEDLINE, EMBASE, Cochrane, WHO COVID-19 databases from inception to 15/06/2020 and medRxiv. No language restriction. Newcastle-Ottawa Scale (NOS) and GRADE framework were utilised to assess the risk of bias and certainty of evidence. PROSPERO CRD42020188421.

Results

Seventy-two articles (59 cohort studies with 17,950,989 participants, 13 ecological studies; 54 US-based, 15 UK-based; 41 peer-reviewed) were included for systematic review and 45 for meta-analyses. Risk of bias was low: median NOS 7 of 9 (interquartile range 6-8). Compared to White ethnicity, unadjusted all-cause mortality was similar in Black (RR: 0.96 [95% CI: 0.83-1.08]) and Asian (RR: 0

SUBMITTER: Raharja A 

PROVIDER: S-EPMC7659894 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature