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Immunotoxicity and intestinal effects of nano- and microplastics: a review of the literature.


ABSTRACT:

Background

Together with poor biodegradability and insufficient recycling, the massive production and use of plastics have led to widespread environmental contamination by nano- and microplastics. These particles accumulate across ecosystems - even in the most remote habitats - and are transferred through food chains, leading to inevitable human ingestion, that adds to the highest one due to food processes and packaging.

Objective

The present review aimed at providing a comprehensive overview of current knowledge regarding the effects of nano- and microplastics on intestinal homeostasis.

Methods

We conducted a literature search focused on the in vivo effects of nano- and microplastics on gut epithelium and microbiota, as well as on immune response.

Results

Nume

SUBMITTER: Hirt N 

PROVIDER: S-EPMC7661204 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature